Mannitol

Indications

Mannitol Injection 20% is indicated for use as an osmotic diuretic in canine species. Mannitol is essentially inert metabolically. When given parenterally, it is freely filtered at the glomerulus which produces osmotic diuresis as more than 90% of the mannitol injected escapes reabsorption. Each 100 mL Contains: Mannitol USP...................................20 g Water for Injection...........................q.s. This solution contains 1098 m0smols/Liter

Dosage and Administration

The usual canine dosage administered intravenously is 1.5 - 2.0 g per Kg body weight given over a 30 minute period. This is approximately 3.4-4.5 mL/lb of body weight. Note: Crystals of mannitol may form in a 20% saturated solution of mannitol. Dissolve the crystals by warming in hot water or autoclaving for 15 minutes. Cool to body temperature before administering. This is a single dose vial that contains no preservatives. Use entire contents when first opened.

Storage

Store at temperatures between 15°and 30°C (59°-86°F) Made in the USA of U.S. and imported materials. Distributed by: MWI Boise, ID 83705 www.VetOne.net Caution: Federal law restricts this drug to use by or on the order of a licensed veterinarian. FOR ANIMAL USE ONLY KEEP OUT OF THE REACH OF CHILDREN Questions? Call 859-254-1221 or toll-free 800-621-8829 NDC 13985-052-15 VETONE Mannitol 20% Injection Sterile Solution For animal use only. Keep out of reach of children. CAUTION: Federal law restricts this drug to use by ot on the order of a licensed veterinarian. V1 501050 Net Contents: 100mL Mannitol.jpg

FDA adverse event reports

The FDA Center for Veterinary Medicine publishes the adverse event reports it receives through openFDA. The counts below are the reports naming mannitol as an active ingredient for each species this label names, as returned on 2026-09-16, coded by the VeDDRA reaction term the reporter chose. Reactions are counted per report, so one report can appear under several terms.

These are counts, not rates. Reporting is voluntary, the number of animals treated is not known, and a widely used product accumulates reports for that reason alone. A report records that an event followed a dose; it does not establish that the product caused it. The counts say nothing about how one product compares with another.