Sulfadimethoxine

Indications

Albon is indicated for the treatment of respiratory, genitourinary tract, enteric, and soft tissue infections in dogs and cats: tonsillitis pharyngitis bronchitis pneumonia cystitis nephritis metritis pyometra pustular dermatitis anal gland infections abscesses wound infections bacterial enteritis canine salmonellosis bacterial enteritis associated with coccidiosis in dogs when caused by streptococci, staphylococci, escherichia, salmonella, klebsiella, proteus or shigella organisms sensitive to sulfadimethoxine. Limitations: Sulfadimethoxine is not effective in viral or rickettsial infections, and as with any antibacterial agent, occasional failures in therapy may occur due to resistant microorganisms. The usual precautions in sulfonamide therapy should be observed.

Dosage and Administration

Initial Dose: 25 mg/lb (55 mg/kg) of animal body weight. Subsequent Daily Doses: 12.5 mg/lb (27.5 mg/kg) of animal body weight. Dogs and cats should receive 1 teaspoonful of Albon Oral Suspension 5% per 10 lb of body weight (25 mg/lb or 55 mg/kg) as an initial dose, followed by 1/2 teaspoonful per 10 lb of body weight (12.5 mg/lb or 27.5 mg/kg) every 24 hours thereafter. Representative weights and doses are indicated in the following table: Animal Weight Initial Dose 25 mg/lb (55 mg/kg) Subsequent Daily Doses 12.5 mg/lb (27.5 mg/kg) 5 lb (2.2 kg) 1/2 tsp (2 1/2 mL) 1/4 tsp (1 1/4 mL) 10 lb (4.5 kg) 1 tsp (5 mL) 1/2 tsp (2 1/2 mL) 20 lb (9.1 kg) 2 tsp (10 mL) 1 tsp (5 mL) 40 lb (18.2 kg) 4 tsp (20 mL) 2 tsp (10 mL) 80 lb (36.4 kg) 8 tsp (40 mL) 4 tsp (20 mL) Treatment may be initiated with Albon Injection 40% to obtain effective blood levels almost immediately or to facilitate treatment of the fractious animal. Length of treatment depends on the clinical response. In most cases treatment for 3–5 days is adequate. Treatment should be continued until the animal is asymptomatic for 48 hours. TOXICITY AND SAFETY Data regarding acute and chronic toxicities of sulfadimethoxine indicate the drug is very safe. The LD 50 in mice is greater than 2 g/kg of body weight when administered intraperitoneally and greater than 16 g/kg when administered orally. In dogs receiving massive single oral doses of 3.2 g/kg of body weight, diarrhea was the only adverse effect observed. Dogs given 160 mg/kg of body weight orally daily for 13 weeks showed no signs of toxicity.

Precautions

During treatment period, make certain that animals maintain adequate water intake. If animals show no improvement within 2 or 3 days, reevaluate your diagnosis.

Description

Albon is a low-dosage, rapidly absorbed, long-acting sulfonamide, effective for the treatment of a wide range of bacterial infections commonly encountered in dogs and cats. Sulfadimethoxine is a white, almost tasteless and odorless compound. Chemically, it is N 1 -(2,6-dimethoxy-4-pyrimidinyl) sulfanilamide. The structural formula is: Chemical Structure

Storage

Store at controlled room temperature 15°–30°C (59°–86°F).

Other labels for this ingredient

These labels are also stored for the same active ingredient. They are not identical to the one reprinted above, and each is listed by product and set id rather than merged with it.

• ALBON ® Tablets, Zoetis Inc.. Set id 71a27a8a-038b-4b6d-8237-d6b58ddf9dc8.

FDA adverse event reports

The FDA Center for Veterinary Medicine publishes the adverse event reports it receives through openFDA. The counts below are the reports naming sulfadimethoxine as an active ingredient for each species this label names, as returned on 2026-09-16, coded by the VeDDRA reaction term the reporter chose. Reactions are counted per report, so one report can appear under several terms.

These are counts, not rates. Reporting is voluntary, the number of animals treated is not known, and a widely used product accumulates reports for that reason alone. A report records that an event followed a dose; it does not establish that the product caused it. The counts say nothing about how one product compares with another.